I make videos using obs to capture the screen and also a cam and audio. I’m sure you have seen that sort of thing.
To check its in sync, I watch the recording and look for lip sync.
To answer the other part of your question, yes the only settings I could play with were resolution and fps.
I’ve never done live streaming so cannot comment.
From my I.T. background I can say there would be no difference betwen writing data to a file on a disk or a handle on the network. At that stage it is only data being moved around with the writier having no understanding of what the data is.